Struggling with chronic anxiety can take a serious toll—draining your energy, disrupting focus and sleep, and diminishing your overall well-being. At Hydrate Medical in Charlotte, NC, our NAD+ Therapy offers a medically supervised, provider-led approach to help support your body’s natural stress response and neurochemical balance.
We offer both NAD+ IV infusions and convenient subcutaneous (SubQ) injections as part of a supportive wellness plan. While not a substitute for professional mental health treatment, NAD+ therapy can serve as a powerful adjunct—promoting cellular repair and metabolic function to help you feel more balanced and resilient.
Important: NAD+ therapy is not a treatment for diagnosed anxiety disorders and should not replace care from a mental health professional. If you’re experiencing a mental health crisis, call or text 988 for immediate support.
NAD+ is essential for energy production within cells, supports mitochondrial function, and plays a role in the creation of neurotransmitters—all of which are involved in mood and stress regulation. Some studies suggest that low NAD+ levels may be linked to anxiety symptoms, especially in cases involving chronic fatigue or long-term stress.
A study by Alegre and colleagues in 2010 explored oral NADH supplements in patients with chronic fatigue syndrome. The double-blind, placebo-controlled trial showed a statistically significant reduction in anxiety scores for the NADH group (p < 0.05). While the participants had chronic fatigue, the observed decrease in anxiety suggests a potential benefit for those experiencing similar symptoms.
A 2024 systematic review published in the American Journal of Physiology examined multiple randomized clinical trials. It found that NADH and NAD+ precursor supplements were generally well tolerated and associated with lower anxiety symptoms and better quality of life outcomes.
Important context: Most of the current research focuses on individuals with chronic fatigue or studies where anxiety was a secondary outcome. There is a lack of large, targeted trials specifically assessing NAD+ therapy for anxiety disorders. While early findings are encouraging, more research is needed to fully understand the potential role of NAD+ in managing anxiety.
Comprehensive cellular support delivered in a quiet, comfortable setting designed to promote relaxation during treatment.
A quicker option for maintenance or ongoing support.
Brief in-office visits
Relaxing, private lounge setting
Infusion rate adjusted based on your comfort
Continuous monitoring by experienced nursing staff
Optional comforts like streaming, refreshments, or a quiet environment
Most individuals tolerate treatment well, but some may experience nausea, flushing, headache, or a temporary increase in anxiety. These symptoms are often manageable by adjusting the infusion rate.
NAD+ therapy is not a cure for anxiety. Anxiety is a complex condition influenced by brain chemistry, life experiences, trauma, and genetics.
We offer metabolic and cellular support services. We do not diagnose or treat mental health conditions. If you are already working with a mental health provider, we encourage open communication and, with your permission, can collaborate with your care team to support safe, integrated treatment.
NAD+ Treatments